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No skin reactions, but Elucence Moisture Balance makes me sneeze sumthin' fierce! I keep buying it though because it's conditioning effect lasts consecutive days.
I believe I had a small reaction to MSM when I first starting using it, but they subsided after awhile. I had a bad flaking reaction to Surge, but I believe I was using too much at first. I like the product and I am still using it, I just modified how much I use now and I'm doing fine.